Wednesday, 21 June 2017

World Sickle Cell Day

Better late than not at all... 

Monday 19th June was World Sickle Cell Day and our local CLAHRC has been conducting a survey, which found that a greater awareness of sickle cell disease would improve patients' experience, and that staff in emergency settings had a relatively poor knowledge.

They have produced an infographic.

To improve your clinicians' and practitioners' knowledge, here are some resources:


Professor Simon Dyson, De Montfort University,  especially the Resources and Information page, which lists UK organisations and resources for schools.  Professor Dyson has also produced some open educational resources.

Rest of the UK

Clinical Knowledge Summaries for an evidence based summary.

HealthTalk for patient experiences of screening.

NHS Choices for an overview and links to other NHS resources.

NICE material is included in the set relating to blood conditions - a clinical guideline (CG143) and a quality standard (QS58)

Sickle Cell Society - UK based patient support organisation

Rest of the world

emDOCS - The sickle cell patient: ED management of acute complications.   Detailed discussion from this US based emergency medicine blog.  

Life in the Fast Lane (LITFL) - Sickle cell crisis.  Another blog for emergency medicine and critical care, based in Australia and New Zealand.

MedGen for everything genetic.

Wednesday, 14 June 2017

Bicuspid aortic valve - Medline search strategy

The aortic valve should have three "leaflets", so is "tricuspid".    Sometimes it has only two, because two are fused together, and then it is "bicuspid".

Bicuspid aortic valve (BAV) is a congenital condition.  It is linked to aortic aneurysms.

How to find literature about BAV?

There is no MeSH term for bicuspid aortic valve, although there is a "supplementary concept" Bicuspid aortic valve.  This is searchable in PubMed as [Supplementary Concept], but as far as I can work out, is not searched or searchable in HDAS.

In PubMed, the freetext term "bicuspid aortic valve" maps to the supplementary concept.

So is it enough to rely just on the phrase "bicuspid aortic valve(s)"?   I think not, because: 

a) I have seen phrases like "bicuspid and tricuspid aortic valve" and "bicuspid aortopathy".  The latter, I think, relates to the aorta, not the valve, but the aorta as it is affected by the valve.  

b) Perhaps there is literature where BAV is indexed under Heart Defects, Congenital/ and a MeSH term relating to the aortic valve but where phrases describing BAV itself are not used.

I was working on a search about fusion patterns in BAV, that is, which leaflet is joined to which, and that gave me some more terms.

So, taking all that into account, here is my draft of a search strategy for Medline via HDAS:

1. ("bicuspid aort*").ti,ab
2. (BAV).ti,ab
5. exp "AORTIC VALVE STENOSIS"/         
8. (fusion OR fused OR fusing OR morphol* OR morphotyp* OR phenotyp* OR habitus OR raphe).ti,ab
9. ("right noncoronary" OR "left noncoronary" OR "right left" OR "left right").ti,ab
10. ((left OR right) ADJ2 "non coronary").ti,ab
11. (classif* OR pattern* OR commissur*).ti,ab
12. 1 OR 2
13. (3 OR 4 OR 5) AND 6
14. 3 AND 7
15. (8 OR 9 OR 10 OR 11)
16. ("aortic valve*").ti,ab
17. (3 AND 15)
18. (15 AND 16)

19. (12 OR 13 OR 14 OR 17 OR 18)

Lines 3 - 7 are an attempt to capture the way BAV is indexed in the absence of a single MeSH heading.

Lines 8 - 11 describe the fusion patterns and other features of a BAV, although some words are possibly too general ("pattern" for example could be referring to something else, not the valve).

On 14th June 2017, line 1 found 2454, line 19 found 12693.    How many of these extra ones are relevant, but not found in set 1 or 2, is not clear.


12 or 13 or 14 

would be enough (this finds 9939).

All of this, of course needs, testing.  

Perhaps which strategy you use (assuming you think it worth using!) would depend why you are searching, and if there were other aspects to the search, it may matter less.

Tuesday, 23 May 2017

International Clinical Librarian Conference - Programme released

9th International Clinical Librarian Conference, in Leicester UK.
21st to 22nd September 2017

We are pleased to announce the programme for the next ICLC conference, organised by University Hospitals of Leicester NHS Trust.

The conference will be held at Leicester Racecourse, in the vibrant multicultural city of Leicester. Leicester is only 66 minutes away from London via train, and Stratford Upon Avon is only an hour away by car. Leicester is also the home of world famous sports teams, so you could stay on after the conference for some exciting sports viewing!

Accommodation suggestions can be found here and there is free parking at the conference venue.

Monday, 22 May 2017

NEJM Group announces a new website for librarians

Announcement from the New England Journal of Medicine:

You’ll find articles that share the expertise of leading medical librarians, take you behind the scenes of products and events at NEJM Group, and provide resources to help your community take full advantage of our offerings.

Please explore our new site and be sure to register on the home page for an email alert to let you know when new articles are posted.

Friday, 19 May 2017

International Clinical Trials Day

James Lind (1716-1794), by Sir George Chalmers

Friday May 19th is International Clinical Trials Day.

The NIHR is holding events under the heading "I am Research", to increase public awareness of research.

We compiled a set of webpages for the Hope Clinical Trials Facility, based at the Leicester Royal Infirmary, and the pages include links to information about trials registries, participating in trials, and procedures and reporting guidelines.

Have a browse, on this International Clinical Trials Day.

Why this day?   According to the Association of Clinical Research Professionals site, May 20th 1747 is when James Lind began what was probably the first RCT, investigating scurvy.

The James Lind Library contains material illustrating the development of "fair tests of treatments", and can be browsed by topic.   It has information about Lind's trial here.

Portrait of Lind from

Wednesday, 10 May 2017

Systematic review filter for ProQuest PsycInfo

Looking for systematic reviews, I needed a systematic review filter for ProQuest PsycInfo.  

I had searched other databases for the same project and used SIGN's filters, but SIGN did not have one for PsycInfo and the other PsycInfo ones I had found were for other interfaces.

The idea behind using a filter, and not relying on database publication type limits, is that not every SR is indexed as one, so the filters look for terminology that is common in SRs to identify items that are SRs.

I adapted the University of Texas School of Public Health filter (found via the ISSG Search Filters Resource) for ProQuest.

This was what I came up with:

1. TI,AB,IF((comprehensive* OR integrative OR systematic*) NEAR/3 (bibliographic* OR review* OR literature))

2. TI,AB,IF((meta-analy* or metaanaly* or "research synthesis" or ((information or data) NEAR/3 synthesis) or (data NEAR/2 extract*)))

3. TI,AB,IF(review NEAR/5 (rationale or evidence)) and ME("Literature Review")

4. AB(cinahl or cinhal or (cochrane NEAR/3 trial*) or embase or medline or psyclit or psychlit or pubmed or scopus or "sociological abstracts" or "web of science")

5. ME("systematic review" or "meta analysis")

6. 1 OR 2 OR 3 OR 4 OR 5

The UTSPH filter is one line, but I got muddled with brackets and found it easier to have several lines...   Line 3 does not include the word PsycInfo because (as I discovered!) every reference in the database has that word in the abstract...  

Monday, 30 January 2017

Registration is now open for ICLC 2017

The International Clinical Librarian Conference (ICLC) runs conferences, targeted at Clinical Librarians and any other health librarian who finds the topics covered of interest.

21st to 22nd September 2017
Leicester Racecourse
Leicester LE2 4AL

The International Clinical Librarian Conference is organised by the Clinical Librarian team at University Hospitals of Leicester NHS Trust (UHL) in the United Kingdom.

To find out more information on the UHL team and what they do, please visit their website at

Abstract submissions are also currently being accepted: